Selective inhibition of the gliadin-specific, cell-mediated immune response by transamidation with microbial transglutaminase
نویسندگان
چکیده
منابع مشابه
Abrogation of Immunogenic Properties of Gliadin Peptides through Transamidation by Microbial Transglutaminase Is Acyl-Acceptor Dependent
Wheat gluten confers superior baking quality to wheat based products but elicits a pro-inflammatory immune response in patients with celiac disease. Transamidation of gluten by microbial transglutaminase (mTG) and tissue transglutaminase (tTG) reduces the immunogenicity of gluten; however, little information is available on the minimal modification sufficient to eliminate gliadin immunogenicity...
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ژورنال
عنوان ژورنال: Journal of Leukocyte Biology
سال: 2013
ISSN: 0741-5400
DOI: 10.1189/jlb.0412182